European Iron Club: Metal Based Neurodegenerative Diseases; Figure 10


Superimposed for backbone atoms of residue 8-38 (RMSD = 0.86°A)		Superimposed for backbone atoms of residues 8-25 (RMSD = 0.38°A)

Superimposed for backbone atoms of residues 26-27 (RMSD = 0.048°A)		Superimposed for backbone atoms of residues 23-38 (RMSD = 0.59°A)
Figure 10a Bundle of the best 10 structures of Aβ₄₂ after AMBER minimisation

Figure 10b
Stereo view of the lowest energy structure
coloured according to the electrostatic potential

Figure 10c
Comparison of the shapes of the lowest energy structure of influenza haemagglutinin (A) and of the 1-35 region of the Aβ _(1-42)

Figure 10

CONTENTS
Abstract
1.	Metals in Brain, Metal Transport, Storage and Homeostasis
2.	Oxidative Stress and Redox-Active Metal Ions
3.	Degradation of Cellular Proteins via Proteasomal System
4.	Parkinson's Disease
5.	Alzheimer's Disease
6.	Other Metal-Based Neurodegeneration Diseases
7.	Therapeutic Strategies
References
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