European Iron Club: Metal Based Neurodegenerative Diseases; Figure 04

Figure 4a
Midbrain Lewy body


stained with antibody α-synuclein		stained with antibody ubiquitin

stained with antibody lipids		merge

Figure 4b
Lewy bodies stained with antibodies
α-synuclein, ubiquitin and lipids

A lewy body contains a mass of proteins including synuclein, and is a characteristic feature of Parkinson's disease of neural tissue.

Figure 4

CONTENTS
Abstract
1.	Metals in Brain, Metal Transport, Storage and Homeostasis
2.	Oxidative Stress and Redox-Active Metal Ions
3.	Degradation of Cellular Proteins via Proteasomal System
4.	Parkinson's Disease
5.	Alzheimer's Disease
6.	Other Metal-Based Neurodegeneration Diseases
7.	Therapeutic Strategies
References
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