European Iron Club: Metal Based Neurodegenerative Diseases; Figure 02


2-Alkenals	4-Hydroxy-2-Alkenals	Ketoaldehydes
Figure 2a Structures of reactive aldehydes


Glyoxal	MDA	ONE
Figure 2b: Lipid-peroxidation-specific aldehydes

Figure 2c:
Michel type addition of 4-hydroxynonenol (HNE) to proteins

Figure 2

CONTENTS
Abstract
1.	Metals in Brain, Metal Transport, Storage and Homeostasis
2.	Oxidative Stress and Redox-Active Metal Ions
3.	Degradation of Cellular Proteins via Proteasomal System
4.	Parkinson's Disease
5.	Alzheimer's Disease
6.	Other Metal-Based Neurodegeneration Diseases
7.	Therapeutic Strategies
References
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